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It is no wonder that now the latest idea is to unite prescription medications with the idea that using the combination could have the miraculous results which they so desperately want and in many cases need. Using two separate drugs to shed weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with fat loss and the people that go through it you need to err on the side of caution and let the FDA do its job and demand some study be done so that the public knows the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies have been in business to make money and that they would say anything to keep people on their own medications. Researchers found that participants investing in this drug to get a year, dropped a few pounds within 4 weeks and have kept the body weight off throughout the 56 weeks of the study. Contrave can be a combination in the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs that are made up of several active ingredient, which can make them more potent and safer. Combo-pilling could be the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills has become popular may be the fact that since right now there are no long term prescription diet pills that have been authorized by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and must not be taken in those with seizure disorders. The drug may also raise hypertension and heartbeat, and must not be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure level and pulse rate and must not be used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. From a psychiatric point of view, evidence shows that the ordinary neural mechanism for goal-directed behavior continues to be hijacked from the addiction, and malfunctions such that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus along with the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).