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Using two separate drugs to lose weight can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with fat loss and the those who go through it one should err on the side of caution and let the FDA do its job and demand some investigation be done in order that the public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to earn money and that they would say anything to keep people on the medications. Researchers found that participants using this drug for the year, lost weight within one month and have kept the body weight off through the entire 56 weeks in the study. Contrave can be a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, which might make them more potent and safer. Combo-pilling may be the newest fad or also the newest to come under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular may be the fact that since right now there are no long term prescription slimming capsules that have been licensed by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug can also raise blood pressure levels and pulse rate, and mustn't be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must not used in patients with uncontrolled high blood pressure level, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients on the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking. The most common adverse reactions reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.