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Using two separate drugs to shed weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err assisting caution and allow FDA do its job and demand some study be done so your public knows the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say anything to keep people on the medications. Researchers discovered that participants investing in this drug to get a year, lost excess weight within four weeks and have kept the body weight off through the entire 56 weeks in the study. Contrave can be a combination in the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs that are made up of many active ingredient, that might make them more potent and safer. Combo-pilling is the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular will be the fact that by right now there aren't any long term prescription diet pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug can also raise blood pressure levels and heartbeat, and must not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must not used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients on the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. An independent report published by Gant Daily in April also stated that naltrexone also utilizes kleptomaniacs and gambling addicts, as well. Citing research from your University of Minnesota School of Medicine, Gant Daily reported how the drug works on kleptomaniacs and chronic gamblers in the same way with alcohol and opioid addicts'by blocking the consequences of endorphins, that your brain releases when experiencing craving or compulsions.