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It must be used in combination with a low-calorie diet and physical exercise in order to be effective. Using two separate drugs to lose weight naturally can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err to the side of caution and let the FDA do its job and demand some investigation be done so your public is aware of the side effects and risks of the medications before we bring them. Keep in mind that drug companies have been in business to earn money and that they would say everything to keep people on his or her medications. Researchers found out that participants investing in this drug for the year, dropped a few pounds within a month and have kept the weight off through the entire 56 weeks with the study. Contrave is a combination with the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, that might make them more efficient and safer. Combo-pilling is the newest fad or in addition to this the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills has become popular is the fact that at the time of right now there are not any long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug may also raise blood pressure and heart rate, and mustn't be used in people who have a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must 't be used in patients with uncontrolled high hypertension, along with by you are not heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients which has a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients to the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking. BioCorRx, Inc.'s naltrexone implant isn't any bigger than a thumb and it is inserted beneath the patient's skin by way of a 30-minute, minimally invasive outpatient procedure made by a medical professional. The implant is administered within BioCorRx, Inc.'s Start Fresh Program which can be distributed in several states by independent rehabilitation facilities.