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The drugs, acamprosate (marketing name: Campral) and naltrexone (ReVia) were found to aid those struggling in several phases of recovery. Acamprosate helped manage emotional triggers in people who had already stopped drinking, naltrexone helped manage cravings in heavy drinkers who are looking to stop drinking or recently quit. Using two separate drugs to shed weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you ought to err along the side of caution and permit the FDA do its job and demand some study be done so the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies are in business to generate money and that they would say everything to keep people on his or her medications. Researchers found that participants taking this drug for the year, dropped a few pounds within 4 weeks and have kept the body weight off throughout the 56 weeks in the study. Contrave is really a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of several active ingredient, which can make them more efficient and safer. Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and thus it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular may be the fact that since right now there are no long term prescription diet pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug may also raise hypertension and pulse rate, and really should not be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must not be used in patients with uncontrolled high hypertension, along with by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients towards the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking. From a psychiatric perspective, evidence implies that the ordinary neural mechanism for goal-directed behavior continues to be hijacked from the addiction, and malfunctions in a way that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus as well as the person engages in a "goal-directed behavioral response" that produces a "natural high"(Bostwick & Bucci, 2008).