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Contrave is really a combination from the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs that are made up of many active ingredient, which might make them far better and safer. Combo-pilling may be the newest fad or in addition to this the newest in the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular will be the fact that as of right now there aren't long term prescription diet pills that have been licensed by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug may also raise blood pressure levels and heart rate, and shouldn't be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must stop used in patients with uncontrolled high blood pressure, along with by you are not heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. 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